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Startseite > Forschung > Neuroimmunologie > Publikationsliste

Publikationen

2018

Moser A, Hanssen H, Wandinger KP: Excessively increased CSF glutamate levels in GABAB-receptor antibody associated encephalitis: A case report. J Neurol Sci 2018; 388: 10-11. 

Wandinger KP, Leypoldt F, Junker R: Autoantibody-associated encephalitis. Deut Ärzteblatt 2018; (in press)

Hasselbacher K, Steffen A, Wandinger KP, Brüggemann N: IgLON5 antibodies are infrequent in patients with isolated sleep apnea. Eur J Neurol 2018; 25: e46-e47. doi: 10.1111/ene.13566.

Dulovic M, Schäffer E, Leypoldt F, Balck A, Schaake S, Hinrichs F, Kirchner H, Brüggemann N, Berg D, Lohmann K: A Klinefelter patient with an additional mitochondrial mutation: Implications for genotype-driven treatment and mitochondrial mutational load in different tissues and family members. Parkinsonism Relat Disord 2018; pii: S1353-8020(18)30146-9. doi: 10.1016/j.parkreldis.2018.04.001. Epub 2018 Apr 3.

Jarius S, Ruprecht K, Stellmann JP, Huss A, Ayzenberg I, Willing A, Trebst C, Pawlitzki M, Abdelhak A, Grüter T, Leypoldt F, Haas J, Kleiter I, Tumani H, Fechner K, Reindl M, Paul F, Wildemann B: MOG-IgG in primary and secondary chronic progressive multiple sclerosis: a multicenter study of 200 patients and review of the literature. J Neuroinflammation 2018; 15: 88. "

Heine J, Prüss H, Kopp UA, Wegner F, Then Bergh F, Münte T, Wandinger KP, Paul F, Bartsch T, Finke C: Beyond the limbic system: disruption and functional compensation of large-scale brain networks in patients with anti-LGI1 encephalitis. J Neurol Neurosurg Psychiatry 2018; pii: jnnp-2017-317780. doi: 10.1136/jnnp-2017-317780. Epub 2018 Jun 9.

Mueller SH, Färber A, Prüss H, Melzer N, Golombeck KS, Kümpfel T, Thaler F, Elisak M, Lewerenz J, Kaufmann M, Sühs KW, Ringelstein M, Kellinghaus C, Bien CG, Kraft A, Zettl UK, Ehrlich S, Handreka R, Rostásy K, Then Bergh F, Faiss JH, Lieb W, Franke A, Kuhlenbäumer G, Wandinger KP, Leypoldt F, German Network for Research on Autoimmune Encephalitis (GENERATE): Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis. Ann Neurol 2018; 83: 863-69.

2017

Körtvélyessy P, Breu M, Pawlitzki M, Metz I, Heinze HJ, Matzke M, Mawrin C, Rommer P, Kovacs GG, Mitter C, Reindl M, Brück W, Wandinger KP, Lassmann H, Höftberger R, Leypoldt F: ADEM-like presentation, anti-MOG antibodies, and MS pathology: TWO case reports. Neurol Neuroimmunol Neuroinflamm 2017; 4: e335.  doi: 10.1212/NXI.0000000000000335. eCollection 2017 May.

Miske R, Gross CC, Scharf M, Golombeck KS, Hartwig M, Bhatia U, Schulte-Mecklenbeck A, Bönte K, Strippel C, Schöls L, Synofzik M, Lohmann H, Dettman IM, Deppe M, Mindorf S, Warnecke T, Denno Y, Teegen B, Probst C, Brakopp S, Wandinger KP, Wiendl H, Stöcker W, Meuth SG, Komorowski L, Melzer N: Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration. Neurol Neuroimmunol Neuroinflamm 2017; 4: e307.

Finke C, Prüss H, Heine J, Reuter S, Kopp UA, Wegner F, Then Bergh F, Koch S, Jansen O, Münte, Deuschl G, Ruprecht K, Stöcker W, Wandinger KP, Paul F, Bartsch T: Evaluation of Cognitive Deficits and Structural Hippocampal Damage in Encephalitis with Leicine. Rich, Glioma-Inactivated 1 Antibodies. JAMA Neurol 2017; 74: 50-9.

Haussleiter IS, Wandinger KP, Juckel G: A case of GABAR antibodies in schizophrenia. BMC Psychiatry 2017; 17: 9.

Malviya M, Barman S, Golombeck KS, Planagumà J, Mannara F, Strutz-Seebohm N, Wrzos C, Demir F, Baksmeier C, Steckel J, Falk KK, Gross CC, Kovac S, Bönte K, Johnen A, Wandinger KP, Martín-García E, Becker AJ, Elger CE, Klöcker N, Wiendl H, Meuth SG, Hartung HP, Seebohm G, Leypoldt F, Maldonado R, Stadelmann C, Dalmau J, Melzer N, Goebels N: NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody. Ann Clin Trans Neurol 2017; 4: 768-83.

Hahn S, Trendelenburg G, Scharf M, Denno Y, Brakopp S, Teegen B, Probst C, Wandinger KP, Buttmann M, Haarmann A, Szabados F, vom Dahl M, Kümpfel T, Eichhorn P, Gold HJ, Paul, F, Jarius S, Melzer N, Stöcker W, Komorowsk L: Identification of the flotilin-1/2 heterocomplex as a target of autoantibodies in bona fide multiple sclerosis. J Neuroinflamm 2017; 14: 123.

Ludwig RJ, Vanhoorelbeke K, Leypoldt F, Kaya Z, Bieber K, McLachlan S, Komorowski L, Luo J, Marques O, Hammers CM, Lindstrom JM, Lamprecht P, Fischer A, Riemekasten G, Tersteeg C, Sondermann P, Rapoport B, Wandinger KP, Probst C, El Beidaq A, Schmidt E, Verkman A, Manz RA, Nimmerjahn F. Mechanisms of autoantibody-induced pathology. Front Immunol 2017; 8: 603.

Hennes EM, Baumann M, Schanda K, Anlar B, Bajer-Kornek B, Blaschek A, Brantner-Inthaler S, Diepold K, Eisenkölbl A, Gotwald T, Kuchukhidze G, Gruber-Sedlmayr U, Häusler M, Höftberger R, Karenfort M, Klein A, Koch J, Kraus V, Lechner C, Leiz S, Leypoldt F, Mader S, Marquard K, Poggenburg I, Pohl D, Pritsch M, Raucherzauner M, Schimmel M, Thiels C, Tibussek D, Vieker S, Zeches C, Berger T, Reindl M, Rostásy K, BIOMARKER Study Group: Prognostic relevance of MOG antibodies in children with an acquired demyelinating syndrome. Neurology 2017; 89: 900-8.

Gaig C, Graus F, Compta Y, Högl B, Bataller L, Brüggemann N, Giordana C, Heidbreder A, Kotschet K, Lewerenz J, Macher S, Marti  MJ, Montojo T, Perez-Perez J, Puertas , Seitz C, Simabukur M, Tellez N, Wandinger KP, Iranzo A, Ercilla G, Sabater L, Santamaria J, Dalmau J: Clinical manifestations of the anti-IgLON5 disease. Neurology 2017; 88: 1746-3.

Koch M, Furtado JD, Falk K, Leypoldt F, Mukamal KJ, Jensen MK: Apolipoproteins and their subspecies in human cerebrospinal fluid and plasma. Alzheimers Dement (Amst) 2017; 6: 182-7. 

Finke C, Prüss H, Heine J, Reuter S, Kopp U, Wegner F, Berg F, Koch S, Jansen O, Münte T, Deuschl G, Ruprecht K, Stöcker W, Wandinger KP, Paul F, Bartsch T:  Evaluation of cognitive deficits and structural hippocampal damage in encephalitis with leucine-rich, glioma inactivated 1 antibodies. JAMA Neurol 2017; 74: 50-9.

Leypoldt F, Magnus, T, Voltz R: Paraneoplastische neurologische Syndrome In: Diener, Gerloff, Dieterich: Therapie und Verlauf neurologischer Erkrankungen. Stuttgart: Kohlhammer 2017; 979-989..

2016

Gersing A.S., Faymonville A.M,. Schwaiger B.J., Leypoldt F., Siemonsen S., Zimmer C., Magnus T., Fiehler J. Quantitative T2* mapping reveals early temporo-spatial dynamics in an ischemic stroke model. J. Neurosci. Methods. 2016 Feb 1;259:83-9. doi: 10.1016/j.jneumeth.2015.11.018. Epub 2015 Nov 29.

Graus F., Titulaer M.J., Balu R., Benseler S., Bien C.G., Cellucci T., Cortese I., Dale R.C., Gelfand J.M., Geschwind M., Glaser C.A., Honnorat J., Höftberger R., Iizuka T., Irani S.R., Lancaster E., Leypoldt F., Prüss H., Rae-Grant A., Reindl M., Rosenfeld M.R., Rostásy K., Saiz A., Venkatesan A., Vincent A., Wandinger K.P., Waters P., Dalmau J. A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol. 2016 Apr;15(4):391-404. doi: 10.1016/S1474-4422(15)00401-9

Gövert F., Witt K., Erro R., Hellriegel H., Paschen S., Martinez-Hernandez E., Wandinger K.P., Deuschl G., Dalmau J., Leypoldt F. Orthostatic myoclonus associated with Caspr2 antibodies. Neurology. 2016 Apr 5;86(14):1353-5. doi: 10.1212/WNL.0000000000002547

Erdur H., Scholz V., Streitz M., Hammer M., Meisel C., Schönemann C., Wandinger K.P., Rosche B. EBNA1 antigen-specific CD8+ Tcells in cerebrospinal fluid of patients with multiple sclerosis. J. Neuroimmunol. 2016 May 15;294:14-7. doi: 10.1016/j.jneuroim.2016.03.010. Epub 2016 Mar 19.

Brüggemann N., Wandinger K.P., Gaig C., Sprenger A., Junghanns K., Helmchen C., Münchau A. Dystonia, lower limb stiffness, and upward gaze palsy in a patient with IgLON5 antibodies. Mov. Disord. 2016 May;31(5):762-4. doi: 10.1002/mds.26608. Epub 2016 Mar 31.

van Sonderen A., Ariño H., Petit-Pedrol M., Leypoldt F., Körtvélyessy P., Wandinger K.P., Lancaster E., Wirtz P.W., Schreurs M.W., Sillevis Smitt P.A., Graus F., Dalmau J., Titulaer M.J. The clinical spectrum of Caspr2 antibody-associated disease. Neurology. 2016 Aug 2;87(5):521-8. doi: 10.1212/WNL.0000000000002917.

Lechner C., Baumann M., Hennes E.M., Schanda K., Marquard K., Karenfort M., Leiz S., Pohl D., Venkateswaran S., Pritsch M., Koch J., Schimmel M., Häusler M., Klein A., Blaschek A., Thiels C., Lücke T., Gruber-Sedlmayr U., Kornek B., Hahn A., Leypoldt F., Sandrieser T., Gallwitz H., Stoffels J., Korenke C., Reindl M., Rostásy K. Antibodies to MOG and AQP4 in children with neuromyelitis optica and limited forms of the disease. J. Neurol. Neurosurg. Psychiatry. 2016 Aug;87(8):897-905. doi: 10.1136/jnnp-2015-311743. Epub 2015 Dec 8.

van Gerpen J.A., Ahlskog J.E., Chen R., Fung V.S., Hallett M., Gövert F., Deuschl G., Leypoldt F. Orthostatic myoclonus associated with Caspr2 antibodies. Neurology. 2016 Sep 13;87(11):1187-8. doi: 10.1212/WNL.0000000000003140.

Jarius S., Ringelstein M., Haas J., Serysheva I.I., Komorowski L., Fechner K., Wandinger K.P., Albrecht P., Hefter H., Moser A., Neuen-Jacob E., Hartung H.P., Wildemann B., Aktas O. Inositol 1,4,5-trisphosphate receptor type 1 autoantibodies in paraneoplastic and non-paraneoplastic peripheral neuropathy. J Neuroinflammation. 2016 Oct 24;13(1):278.

Finke C., Prüss H., Heine J., Reuter S., Kopp U.A., Wegner F., Then Bergh F., Koch S., Jansen O., Münte T., Deuschl G., Ruprecht K., Stöcker W., Wandinger K.P., Paul .F, Bartsch T. Evaluation of Cognitive Deficits and Structural Hippocampal Damage in Encephalitis with Leicine.Rich, Glioma-Inactivated 1 Antibodies. JAMA Neurol. 2016 Nov 21. doi: 10.1001/jamaneurol.2016.4226. [Epub ahead of print]

Lewerenz J., Jarius S., Wildemann B., Wandinger K.P., Leypoldt F. [Autoantibody-associated autoimmune encephalitis and cerebellitis : Clinical presentation, diagnostic work-up and treatment]. Nervenarzt. 2016 Dec;87(12):1293-1299.

Kuhle J., Hardmeier M., Disanto G., Gugleta K., Ecsedi M., Lienert C., Amato M.P., Baum K., Buttmann M., Bayas A, Brassat D, Brochet B, Confavreux C, Edan G, Färkkilä M, Fredrikson S, Frontoni M., D'Hooghe M., Hutchinson M., De Keyser J., Kieseier B.C., Kümpfel T., Rio J., Polman C., Roullet E., Stolz C., Vass K., Wandinger K.P., Kappos L;. A 10-year follow-up of the European multicenter trial of interferon β-1b in secondary-progressive multiple sclerosis.European Long-term Follow-up Study Group in Interferon β-1b in Secondary-progressive Multiple Sclerosis.. Mult Scler. 2016 Apr;22(4):533-43. doi: 10.1177/1352458515594440.

Miske R., Gross C.C., Scharf M., Golombeck K.S., Hartwig M., Bhatia U., Schulte-Mecklenbeck A., Bönte K., Strippel C., Schöls L., Synofzik M., Lohmann H., Dettmann I.M., Deppe M., Mindorf S., Warnecke T., Denno Y., Teegen B., Probst C., Brakopp S., Wandinger K..P, Wiendl H., Stöcker W., Meuth S.G., Komorowski L., Melzer N. Neurochondrin is a neuronal target antigen in autoimmune cerebellar degeneration. Neurol Neuroimmunol Neuroinflamm. 2016 Dec 5;4(1):e307.

 

2015

Jarius S., Wildemann B., Stoecker W., Moser A., Wandinger, K.P. (2015) Psychotic syndrome associated with antibodies to ARHGAP26 and voltage-gated potassium channels. J. Neuroimmunol., Epub Jul 22

Kuhle J., Hardmeier M., Disanto G., Gugleta K., Ecsedi M., Lienert C., Amato M.P., Baum K., Bayas, A., Brassat D., Brochet B., Confavreux C., Edan G., Färkkilä M., Fasbender P., Fredrikson S., Frontoni M., D’Hooghe M., Hutchinson M., De Keyser J., Kieseier B.,  Kümpfel T., Laaksonen M., Rio J., Polman C., Roullet E., Vass K, Wandinger K.P., Kappos L., and the European Long Term Follow-up Study Group in Interferon β-1b in Secondary-Progressive MS. (2015) 10 year follow-up of the European multicenter trial of interferon β-1b in secondary-progressive MS. Mult. Scler., Epub Sep 11

Höftberger R., van Sonderen A., Leypoldt F., Houghton D., Geschwind M., Gelfand J., Paredes M., Sabater L., Saiz A., Titulaer M.J., Graus F., Dalmau J. (2015) Encephalitis and AMPA receptor antibodies: novel findings in a case series of 22 patients. Neurology 84 (24):2403-12. IF 8.303

Finke C., Kopp U.A., Pajkert A., Behrens J.R., Leypoldt F., Wuerfel J.T., Ploner C.J., Prüss H., Paul F. (2015) Structural hippocampal damage in anti-NMDAR encephalitis. Biological Psychiatry S0006-3223(15)00149-3. IF 9.472

Leypoldt F., Höftberger R.*, Titulaer M.J.*, Armangue T., Gresa-Arribas N., Jahn H.,  Rostasy K.,  Schlumberger W., Meyer T., Wandinger K.P., Rosenfeld M., Graus F., Dalmau J. (2015) CXCL13 is a biomarker of response to treatment and outcome in anti-NMDA-receptor encephalitis. JAMA Neurol. 72(2):180-6. IF 7.685   *gleichberechtigte Autorenschaft

Planagumà J.*, Leypoldt F.*, Mannara F., Gutiérrez-Cuesta J.,  Martín-García E., Aguilar E., Titulaer M.J., Jain A., Balice-Gordon R., Lakadamyali M., Graus F., Maldonado R. and Dalmau J. (2015) Human N-Methyl-D-aspartate receptor antibodies alter memory and behavior in mice. Brain 138(Pt 1):94-109. IF: 9.915  *gleichberechtigte Autorenschaft

2014

Doss S*., Wandinger K.P.*, Hyman B., Panzer J., Synofzik M., Dickerson B., Mollenhauer B., Scherzer C.R., Ivinson A.J., Finke C., Schöls L., Müller vom Hagen J., Jahn H., Höltje M., Biswal B.B., Harms L. Ruprecht K., Buchert R., Höglinger G.U., Oertel W.H., Unger M.M., Priller J., Spruth E.J., Paul F., Meisel A., Lynch D., Dirnagl U., Endres M., Teegen B., Probst C., Komorowski L., Stöcker W., Dalmau J., Prüss H. (2014) High prevalence of NMDA receptor IgA/IgM antibodies in different types of dementia. Ann. Clin. Translat. Neurol. 1:, published online: 18 OCT 2014  *gleichberechtigte Autorenschaft

Leypoldt F., Höftberge, R., Titulaer M.J., Armangue T., Gresa-Arribas N., Jahn H., Rostasy K., Schlumberger W., Meyer T., Wandinger K.P., Graus F., Dalmau J. (2014) Investigations on CXCL13 in anti-NMDA receptor encephalitis, a potential biomarker of treatment response. JAMA Neurology, 72:180-186

Malter M.P., Frisch C., Schoene-Bake J.C., Helmstaedter C., Wandinger K.P., Stoecker W., Urbach H., Surges R., Elger C.E., Vincent A.V., Bien C.G. (2014) Outcome of limbic encephalitis with VGKC complex antibodies related to antigenic specificity. J. Neurol., 261:1695-1705.

Leypoldt F., Wandinger K.P. (2014) Paraneoplastic neurological syndromes. Clinical and Experimental Immunology, 175:336-348

Titulaer M.J., Höftberger R., Lizuka T., Leypoldt F., McCracken L., Cellucci T., Benson L.A., Shu H., Irioka T., Hirano M., Singh G., Calvo A.C., Kaida K., Morales P.S., Wirtz P.W., Yamamoto T., Reindl M., Rosenfeld M.R., Graus F., Saiz A., Dalmau J. (2014) Overlapping demyelinating syndromes and anti-NMDA receptor encephalitis. Ann Neurol. 75(3):411-28. IF: 11.193

Gresa-Arribas N., Titulaer M.J., Torrents A., Aguilar E., McCracken L., Leypoldt F., Gleichman A.J., Balice-Gordon R., Rosenfeld M.R., Lynch D., Graus F., Dalmau J. (2014) Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study. Lancet Neurol 13(2):167-77. doi: 10.1016/S1474-4422(13)70282-5. IF: 23.930

Armangue T.*, Leypoldt F.*, Málaga I.,  Raspall-Chaure M., Marti I., Nichter C., Pugh J., Vicente-Rasoamalala M., Lafuente-Hidalgo M., Macaya A., Ke M., Titulaer M.J., Höftberger R., Sheriff H., Glaser C., Dalmau J. (2014) Herpes Simplex Virus Encephalitis is a Trigger of Brain Autoimmunity. Ann Neurol. 75(2):317-23. doi: 10.1002/ana.24083. IF 11.193

Bogner S., Bernreuther C., Matschke J., Barrera-Ocampo A., Sepulveda-Falla D., Leypoldt F., Magnus T., Haag F., Bergmann M., Brück W., Vogelgesang S., Glatzel M. (2014) Immune Activation in Amyloid-β-Related Angiitis Correlates with Decreased Parenchymal Amyloid-β Plaque Load. Neurodegener Dis 13(1):38-44. doi: 10.1159/000352020. IF 3.410

Neuromyelitis Optica Study Group (NEMOS). (2014) Update on the diagnosis and treatment of neuromyelitis optica. Recommendations of the Neuromyelitis Optica Study Group (NEMOS). J Neurol, 261:1-16

2013

Tillack K., Naegele M., Haueis C., Schippling S., Wandinger K.P., Marti, R., Sospedra M. (2013) Gender differences in circulating levels of neutrophil extracellular traps in serum of multiple sclerosis patients. J. Neuroimmunol., Epub Jun 1

Jarius S., Martinez-Garcia P., Hernandez A.L., Brase J.C., Borowski K., Regula J.U., Meinck H.M., Stöcker W., Wildemann B., Wandinger K.P., (2013) Two new cases of anti-Ca (anti-ARHGAP26/GRAF) autoantibody-associated cerebellar ataxia. J. Neuroinflamm. 10:7 doi:10.1186/1742-2094-10-7

Hansen H.C., Klingbeil C., Dalmau J., L, W., Weißbrich B., Wandinger K.P. (2013) Persistent intrathecal antibody synthesis 15 years after recovering from anti-NMDAR encephalitis. JAMA Neurol., 70:117-119

Leypoldt F., Gelderblom M., Schöttle D., Hoffmann S., Wandinger K.P. (2013)  Recovery from severe frontotemporal dysfunction at 3 years after NMDA receptor antibody encephalitis. J. Clin. Neurosci., Epub Jan 10

Steiner J., Walter M., Glanz W., Sarnyai Z., Bernstein H.G., Vielhaber S., Kästner A., Skalej M., Jordan W., Schiltz K., Klingbeil C., Wandinger K.P. , Bogerts B., Stoecker W. (2013) Increased prevalence of diverse NMDA receptor antibodies in patients with an initial diagnosis of schizophrenia: Specific relevance of IgG NR1a antibodies for distinction from N-Methy-D-Aspartate glutamate receptor encephalitis. JAMA Psychiatry, Epub Jan 23

Leypoldt F., Wandinger,K.P., Bien C.G., Dalmau J. (2013) Autoimmune Encephalitis. European Neurological Review

Finke C., Kopp U.A., Scheel M., Pech L.M., Soemmer C., Schlichting J., Leypoldt F., Brandt A.U., Wuerfel J., Probst C., Ploner C.J., Prüss H., Paul F. (2013) Functional and structural brain changes in anti-N-methyl-D-aspartate receptor encephalitis. Ann Neurol 74(2):284-296. doi: 10.1002/ana.23932. IF 11.193

Neuromyelitis Optica Study Group (NEMOS). (2013) Contribution of spinal cord biopsy to diagnosis of aquaporin-4 antibody positive neuromyelitis optica spectrum disorder. Mult. Scler., Epub Nov 5

2012

Prüss H., Finke C., Höltje M., Hofmann J., Klingbeil C., Probst C., Borowski K., Ahnert-Hilger G., Harms L., Schwab J.M., Ploner C.J., Komorowski L., Stoecker W., Dalmau J., Wandinger K.P. (2012) NMDA receptor antibodies in herpes simplex encephalitis. Ann. Neurol. 72:902-911

Kraus P.D., Wolff D., Grauer O., Angstwurm K., Jarius S., Wandinger K.P., Holler E., Schulte-Mattler W., Kleiter I. (2012) Muscle cramps and neuropathies in patients with allogenic hematopoitic stem cell transplantation and graft-versus-host disease. PLoS  ONE,  Epub Sep 17

Haussleiter I.S., Emons B., Schaub M., Borowski K., Brüne M., Wandinger K.P., Juckel G. (2012) Investigation of antibodies against synaptic proteins in a cross-sectional cohort  of psychotic patients. Schizophr. Res., Epub May 28

von Glehn F., Jarius S., Penalva de Oliviera A.C., Brandao C.O., Faria, A.S., Damasceno A., Casseb J., Moraes A.S., Longhini A.L., Wandinger K.P., Damasceno B.P., Wildemann B., Santos L.M.B. (2012) Aquaporin-4 antibodies are not related to HTLV-1 associated myelopathy. PLoS ONE, 7:e39372

Prüss H., Höltje M., Maier N., Gomez A., Buchert R., Harms L., Ahnert-Hilger G., Schmitz D., Terborg C., Kopp U., Klingbeil C., Probst C., Kohler S., Schwab J.M., Stoecker W., Dalmau J., Wandinger K.P. (2012) IgA NMDA receptor antibodies are markers of synaptic immunity in slow cognitive impairment. Neurology, 78:1743-1753.

Jarius S., Paul F., Franciotta D., de Seze J., Münch C., Salvetti M., Ruprecht K., Liebetrau M., Wandinger K.P., Akman-Demir G., Melms A., Kristoferitsch W., Wildemann B. (2012) Neuromyelitis optica spectrum disorders in patients with myasthenia gravis: ten new aquaporin-4 antibody positive cases and a review of the literature. Multiple Sclerosis 18:1135-1143.

Jarius S., Wandinger K.P., Borowski K., Stoecker W., Wildemann B. (2012)  Antibodies to CV2/CRMP5 in neuromyelitis optica-like disease: a case associated with prostate cancer and review of the literature. Clin. Neurol. Neurosurg. 114:331-335.

Leypoldt F., Wandinger K.P., Voltz R. (2012) Neues bei paraneoplastischen Syndromen in der Neurologie. Akt.Neurologie, doi 10.1055/s-0032-1304305

Gelderblom M., Weymar A., Bernreuther C., Velden J., Arunachalam P., Steinbach K., Orthey E., Arumugam T.V., Leypoldt F., Simova O., Thom V., Friese M., Prinz I., Hölscher C., Glatzel M., Korn T., Gerloff C., Tolosa E., Magnus T. (2012) Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke. Blood 120:3793–3802. IF: 9.898

Leypoldt F., Buchert R., Kleiter I., Marienhagen J., Gelderblom M., Magnus T., Dalmau J., Gerloff C., Lewerenz J. (2012) FDG-PET in anti-N-methyl-D-aspartate receptor encephalitis: Distinct pattern of disease. JNNP 83(7):681-6. IF: 4.764

Gelderblom M.*, Leypoldt F.*, Lewerenz J., Birkenmayer G., Orozco D., Ludewig P., Thundyil J., Arumugam T.V., Gerloff C., Tolosa E., Maher P., Magnus T. (2012) The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice. J Cereb Blood Flow Metab 32(5):835-43. IF: 5.008   *gleichberechtigte Autorenschaft

Radue E.W., O'Connor P., Polman C.H., Hohlfeld R., Calabresi P., Selmaj K., Mueller-Lenke N., Agoropoulou C., Holdbrook F., de Vera A., Zhang-Auberson L., Francis G., Burtin P., Kappos L.; FTY720 Research Evaluating Effects of Daily Oral  Therapy in Multiple Sclerosis (FREEDOMS) Study Group. (2012) Impact of fingolimod therapy on magnetic resonance imaging outcomes in patients with multiple sclerosis. Arch. Neurol. 69:1259-1269.

Devonshire V., Havradova E., Radue E.W., O’Connor P., Zhang-Auberson L., Agoropoulou C., Häring D.A., Francis G., Kappos L; FREEDOMS  study group. (2012) Relapse and disability outcomes in patients with multiple sclerosis treated with fingolimod: subgroup analyses of the double-blind, randomised, placebo-controlled FREEDOMS study. Lancet Neurol., 11:420-428.

Jarius S. et al.; Neuromyelitis optica study group (2012) Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients. J. Neuroinflamm. 9:14 doi:10.1186/1742-2094-9-14