Ausgewählte Publikationen/ Selected key publications

PMID: 35182548 Blood transcriptome profiling identifies 2 candidate endotypes of atopic dermatitis - PubMed (nih.gov)

PMID: 34698371, Tralokinumab plus topical corticosteroids in adults with severe atopic dermatitis and inadequate response to or intolerance of ciclosporin A: a placebo-controlled, randomized, phase III clinical trial (ECZTRA 7) - PubMed (nih.gov)

PMID: 34387406, The power and potential of BIOMAP to elucidate host-microbiome interplay in skin inflammatory diseases - PubMed (nih.gov)

PMID: 33733457 Host traits, lifestyle and environment are associated with human skin bacteria - PubMed (nih.gov)

Möbus L, Rodriguez E, Harder I, Schwarz A, Wehkamp U, Stölzl D, Boraczynski N, Gerdes S, Litman T, Kleinheinz A, Abraham S, Heratizadeh A, Handrick C, Haufe E, Schmitt J, Werfel T, Weidinger S. Elevated NK-cell transcriptional signature and dysbalance of resting and activated NK cells in atopic dermatitis. J Allergy Clin Immunol. 2020

Silverberg JI, Toth D, Bieber T, Alexis AF, Elewski BE, Pink AE, Hijnen D, Jensen TN, Bang B, Olsen CK, Kurbasic A, Weidinger S. Tralokinumab plus topical corticosteroids for the treatment of moderate-to-severe atopic dermatitis: results from the double-blind, randomized, multicentre, placebo-controlled phase III ECZTRA 3 trial. Br J Dermatol. 2020

Emmert H, Baurecht H, Thielking F, Stölzl D, Rodriguez E, Harder I, Proksch E, Weidinger S. Stratum corneum lipidomics analysis reveals altered ceramide profile in atopic dermatitis patients across body sites with correlated changes in skin microbiome. Exp Dermatol. 2020

Möbus L, Rodriguez E, Harder I, Stölzl D, Boraczynski N, Gerdes S, Kleinheinz A, Abraham S, Heratizadeh A, Handrick C, Haufe E, Werfel T, Schmitt J, Weidinger S.  Atopic dermatitis displays stable and dynamic skin transcriptome signatures. J Allergy Clin Immunol. 2020

Abraham S, Haufe E, Harder I, Heratizadeh A, Kleinheinz A, Wollenberg A, Weisshaar E, Augustin M, Wiemers F, Zink A, Biedermann T, von Kiedrowski R, Hilgers M, Worm M, Pawlak M, Sticherling M, Fell I, Handrick C, Schäkel K, Staubach P, Asmussen A, Schwarz B, Bell M, Neubert K, Effendy I, Bieber T, Homey B, Gerlach B, Tchitcherina E, Stahl M, Schwichtenberg U, Rossbacher J, Buck P, Mempel M, Beissert S, Werfel T, Weidinger S, Schmitt J; TREATgermany study group. Implementation of dupilumab in routine care of atopic eczema. Results from the German national registry TREATgermany. Br J Dermatol. 2020

Langan SM, Irvine AD, Weidinger S. Atopic dermatitis. Lancet 2020

Tsoi LC, Rodriguez E, Stölzl D, Wehkamp U, Sun J, Gerdes S, Sarkar MK, Hübenthal M, Zeng C, Uppala R, Xing X, Thielking F, Billi AC, Swindell WR, Shefler A, Chen J, Patrick MT, Harms PW, Kahlenberg JM, Perez White BE, Maverakis E, Gudjonsson JE, Weidinger S. Progression of acute-to-chronic atopic dermatitis is associated with quantitative rather than qualitative changes in cytokine responses. J Allergy Clin Immunol. 2019 Dec 28:S0091-6749(19)32610-7

Mucha S, Baurecht H, Novak N, Rodríguez E, Bej S, Mayr G, Emmert H, Stölzl D, Gerdes S, Jung ES, Degenhardt F, Hübenthal M, Ellinghaus E, Kässens JC, Wienbrandt L, Lieb W, Müller-Nurasyid M, Hotze M, Dand N, Grosche S, Marenholz I, Arnold A, Homuth G, Schmidt CO, Wehkamp U, Nöthen MM, Hoffmann P, Paternoster L, Standl M; Early Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium, Bønnelykke K, Ahluwalia TS, Bisgaard H, Peters A, Gieger C, Waldenberger M, Schulz H, Strauch K, Werfel T, Lee YA, Wolfien M, Rosenstiel P, Wolkenhauer O, Schreiber S, Franke A, Weidinger S, Ellinghaus D. - Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression

Weidinger S, Beck LA, Bieber T, Kabashima K, Irvine AD. Atopic Dermatitis. Nat Rev Dis Primers. 2018 Jun 21;4(1):1