Specialized Hematological Diagnostics (Division of Hematology and Oncology)

Cytomorphological evaluation of bone marrow aspirates, blood smears, cytospins of cerebro-spinal fluids, and other aspirates for diagnosis of hematological malignancies and differential diagnosis to reactive lesions

Molecular analyses for diagnosis, stratification, and prognostic evaluation in suspicion of acute and chronic lymphoid and myeloid leukemias, myeloproliferative neoplasms, myelodysplasia, and lymphomas

Multicolor flow based analysis of bone marrow aspirates, peripheral blood, cerebrospinal fluid, and effusions for diagnosis and staging in hematological malignancies

Flow based quantification of T-cell subsets

Molecular quantification of minimal residual disease in acute and chronic lymphatic leukemia, mantle cell lymphoma, follicular lymphoma, multiple myeloma, and chronic myeloid leukemia

Flow based quantification of minimal residual disease in disease in acute and chronic lymphatic leukemia, mantle cell lymphoma, follicular lymphoma and multiple myeloma

Identification and validation of new prognostic or therapeutic molecular markers in Hematological Malignancies

Establishment, standardization, and validation of innovative multicolor flow assays for diagnosis and follow up in hematological malignancies within international cooperations

Establishment, standardization, and validation of innovative molecular methods to quantify minimal residual disease in hematological malignancies within international cooperations

Establishment of high throughput methods to analyse immune gene rearrangements for monitoring of minimal residual disease and perform B- and T-cell repertoire analyses

Characterisation of clonal evolution and selection processes during and after treatment in Lymphoid Neoplasias

Identification of novel escape / resistance mechanisms in hematological malignancies being treated with targeted therapies

Reference laboratory within many national and international phase I-IV treatment studies in acute and chronic lymphocytic leukemia, follicular lymphoma, mantle cell lymphoma, chronic myeloid leukemia, and multiple myeloma

Since 2010 accredited according to DIN EN ISO 15189 by the DAkkS (Deutsche Akkreditierungsstelle)

Member of the EuroFlow Consortium

Member of the EuroClonality Consortium

Member of the EuroClonality NGS Consortium

Member of the EuroMRD Consortium