Publikationen

Isong Assam, Simon P Dierck , Yi Zhao , Michael Jüptner  , Frank-André Siebert , Maaz Zuhayra , Ulf Lützen (2023) Evaluation of sentinel lymph node localization in malignant melanoma by preoperative semiconductor gamma camera and planar lymphoscintigraphy.  J Appl Clin Med Phys 2023 Jun 26; e14077. (IF: 2,100)

Zhao Y, Culman J, Cascorbi I, Nithack N, Marx M, Zuhayra M, Lützen U. (2023) PSMA-617 inhibits proliferation and potentiates the 177Lu-PSMA-617-induced death of human prostate cancer cells. Naunyn Schmiedebergs Arch Pharmacol. 2023 Jun 7. (IF: 3,600)

Devos D, Labreuche J, Rascol O, Corvol JC, Duhamel A, Guyon Delannoy P, Poewe W, Compta Y, Pavese N, Růžička E, Dušek P, Post B, Bloem BR, Berg D, Maetzler W, Otto M, Habert MO, Lehericy S, Ferreira J, Dodel R, Tranchant C, Eusebio A, Thobois S, Marques AR, Meissner WG, Ory-Magne F, Walter U, de Bie RMA, Gago M, Vilas D, Kulisevsky J, Januario C, Coelho MVS, Behnke S, Worth P, Seppi K, Ouk T, Potey C, Leclercq C, Viard R, Kuchcinski G, Lopes R, Pruvo JP, Pigny P, Garçon G, Simonin O, Carpentier J, Rolland AS, Nyholm D, Scherfler C, Mangin JF, Chupin M, Bordet R, Dexter DT, Fradette C, Spino M, Tricta F, Ayton S, Bush AI, Devedjian JC, Duce JA, Cabantchik I, Defebvre L, Deplanque D, Moreau C; FAIRPARK-II Study Group(U. Lützen). (2022) Trial of Deferiprone in Parkinson's Disease. N Engl J Med. 2022 Dec 1;387(22):2045-2055. (IF: 158,500)

Alfteimi A, Lützen U, Helm A, Jüptner M, Marx M, Zhao Y, Zuhayra M. (2022) Automated synthesis of [68Ga]Ga-FAPI-46 without pre-purification of the generator eluate on three common synthesis modules and two generator types. EJNMMI Radiopharm Chem. 2022 Jul 29;7(1):20. (IF: 4,600)

Wrenger R, Jüptner M, Marx M, Zhao Y, Zuhayra M, Caliebe A, Osmonov D, Lützen U. (2022) Pre- and intratherapeutic predictors of overall survival in patients with advanced metastasized castration-resistant prostate cancer receiving Lu-177-PSMA-617 radioligand therapy. BMC Urol. 2022 Jul 4;22(1):96. (IF: 2,000)

Peters JP, Ellermann F, Anikeeva M, Pravdivtsev AN, Saul P, Ferrari A, Lützen U, Zuhayra M, Jansen O, Hövener JB. (2022) [Hyperpolarized 13C magnetic resonance imaging-a window into metabolism : High-resolution images of human metabolism]. Radiologie (Heidelb). 2022 Jun;62(6):486-495. (IF: 0,803)

Anikeeva M, Sangal M, Speck O, Norquay G, Zuhayra M, Lützen U, Peters J, Jansen O, Hövener JB. (2022) [Noninvasive functional lung imaging with hyperpolarized xenon : Breakthrough for diagnostics?]. Radiologie (Heidelb). 2022 Jun;62(6):475-485. (IF: 0,803)

Zuhayra M, Helm A, Ranjan J, Jüptner M, Zhao Y, Marx M, Assam I, Alfteimi A, Lützen U. (2022) A simple, reliable and accurate approach for assessing [131I]-capsule activity leading to significant reduction of radiation exposure of medical staff during radioiodine therapy. Phys Med. 2022 Apr; 96:157-165. (IF: 3,400)

Scheer C, Jüptner M, Maier T, Lützen U. (2022) Unusual accumulation of 177Lu-DOTATATE at the injection site of a COVID-19 vaccination. Nuklearmedizin. 2022 Oct;61(5):410-413.

Schulte DM, Waetzig GH, Schuett H, Marx M, Schulte B, Garbers C, Lokau J, Vlacil AK, Schulz J, Seoudy AK, Schieffer B, Rosenstiel P, Seeger M, Laudes M, Rose-John S, Lützen U, Grote K, Schreiber S. (2022) Case Report: Arterial Wall Inflammation in Atherosclerotic Cardiovascular Disease is Reduced by Olamkicept (sgp130Fc). Front Pharmacol. 2022 Jun 9;13: 758233.

Freudenberg LS, Sewerin P, Ohlerth SM, Pomykala KL, Freudenberg S, Rischpler C, Lützen U. (2022) The future of radiosynoviorthesis: bright or bleak? Q J Nucl Med Mol Imaging. 2022 Dec;66(4):345-351.

Krebs M, Döbber A, Rodat T, Lützen U, Zhao Y, Zuhayra M, Peifer C. (2021) Photopharmacological Applications for Cherenkov Radiation Generated by Clinically Used Radionuclides. Int J Mol Sci. 2021 Aug 20;22(16):9010. (IF: 6.208)

Zhao Y, Lützen U, Gohlke P, Jiang P, Herdegen T, Culman J. (2021) Neuroprotective and antioxidative effects of pioglitazone in brain tissue adjacent to the ischemic core are mediated by PI3K/Akt and Nrf2/ARE pathways. J Mol Med (Berl). 2021 Aug;99(8):1073-1083. (IF: 5,606)

Ulf Lützen (2021) Bildgebung und instrumentelle Diagnostik: Skelettszintigraphie
In Fehm, Hadji, Rody, Solomayer: Referenz Gynäkologie, Georg Thieme Verlag Stuttgart /NewYork, 2021, p. 84-87.

Jüptner M, Lützen U (2021) Die Osteopoikilose als seltene jedoch wichtige Differentialdiagnose zu einer disseminierten Skelettmetastasierung bei einer Patientin mit fortgeschrittenem Mammakarzinom. In: Krug D, Schmalz C, Lützen U, Dunst J (Hrsg.) Neue Entwicklungen in der Strahlentherapie und Onkologie. Band 3. Rönne-Verlag Kiel. ISBN 978-3-00-069921-4. p. 24-27

Nestle U, Schimek-Jasch T, Kremp S, Schaefer-Schuler A, Mix M, Küsters A, Tosch M, Hehr T, Eschmann SM, Bultel YP, Hass P, Fleckenstein J, Thieme A, Stockinger M, Dieckmann K, Miederer M, Holl G, Rischke HC, Gkika E, Adebahr S, König J, Grosu AL; PET-Plan study group(U. Lützen). (2020) Imaging-based target volume reduction in chemoradiotherapy for locally advanced non-small-cell lung cancer (PET-Plan): a multicentre, open-label, randomised, controlled trial. Lancet Oncol. 2020 Apr;21(4):581-592. (IF: 41.316)

Jiang P, Purtskhvanidze K, Kandzia G, Neumann D, Luetzen U, Siebert FA, Roider J, Dunst J. (2020) 106Ruthenium eye plaque brachytherapy in the management of medium sized uveal melanoma. Radiat Oncol. 2020 Jul 29;15(1):183. (IF: 1,358)

Zeissig S, Rosati E, Dowds CM, Aden K, Bethge J, Schulte B, Pan WH, Mishra N, Zuhayra M, Marx M, Paulsen M, Strigli A, Conrad C, Schuldt D, Sinha A, Ebsen H, Kornell SC, Nikolaus S, Arlt A, Kabelitz D, Ellrichmann M, Lützen U, Rosenstiel PC, Franke A, Schreiber S. (2019) Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease. Gut. 2019 Jan;68(1):25-39. (IF: 19,819)

Jüptner M, Marx M, Zuhayra M, Lützen U (2019) Experimental 177Lu-PSMA-617 radioligand therapy in a patient with extended metastasized leiomyosarcoma. Nuklearmedizin. 2019 Aug;58(4):328-330.

Culman J, Mühlenhoff S, Blume A, Hedderich J, Lützen U, Hunt SP, Rupniak NMJ, Zhao Y. (2018) The Hypothalamic-Pituitary-Adrenal Axis and Serotonin Metabolism in Individual Brain Nuclei of Mice with Genetic Disruption of the NK1 Receptor Exposed to Acute Stress. Cell Mol Neurobiol. 2018 Aug;38(6):1271-1281. doi: 10.1007/s10571-018-0594-5 Cell Mol Neurobiol: (IF: 3.811)

Naumann CM, Colberg C, Jüptner M, Marx M, Zhao Y, Jiang P, Hamann MF, Jünemann KP, Zuhayra M, Lützen U. (2018) Evaluation of the diagnostic value of preoperative sentinel lymph node (SLN) imaging in penile carcinoma patients without palpable inguinal lymph nodes via single photon emission computed tomography/computed tomography (SPECT/CT) as compared to planar scintigraphy. Urol Oncol. 2018 Mar;36(3):92.e17-92.e24. (IF: 2,863)

Jiang P, Geenen M, Siebert FA, Bertolini J, Poppe B, Luetzen U, Dunst J, Druecke D. (2018) Efficacy and the toxicity of the interstitial high-dose-rate brachytherapy in the management of recurrent keloids: 5-year outcomes. 2018 May-Jun;17(3):597-600. (IF: 2.010)

Baumann R, Koncz M, Luetzen U, Krause F, Dunst J. (2018) Oligometastases in prostate cancer: Metabolic response in follow-up PSMA-PET-CTs after hypofractionated IGRT. Strahlenther Onkol. 2018 Apr;194(4):318-324. (IF: 2.717)

Jüptner M, Zuhayra M, Assam I, Lützen U (2018) Successful handling of an accidental extravasation of 177Lu-PSMA-617 in the treatment of advanced prostate cancer. Nuklearmedizin. 2018 Apr;57(2):N10-N12. doi: 10.1055/s-0038-1641692.

Ping J, van der Horst C, Kimmig B, Zinsser F, Poppe B, Luetzen U, Juenemann KP, Dunst J, Siebert FA (2017) Interstitial high-dose-rate brachytherapy as salvage treatment for locally recurrent prostate cancer after definitive radiation therapy: Toxicity and 5-year outcome Brachytherapy 2017 16 186-192 (IF: 2.227)

Lützen U, Zhao Y, Lucht K, Zuhayra M, Marx M, Cascorbi I, Culman J (2017) Pioglitazone induces cell growth arrest and activates mitochondrial apoptosis in human uterine leiomyosarcoma cells by a peroxisome proliferator-activated receptor γ-independent mechanism. Naunyn Schmiedebergs Arch Pharmacol. 2017 390 37-48 (IF: 2,376)

Lützen U, Zhao Y, Lucht K, Zuhayra M, Hedderich J, Cascorbi I, Culman J (2017) Activation of the cell membrane angiotensin AT2 receptors in human leimyosarcoma cells induces differentiation and apoptosis by a PPARγ – dependent mechanism. Neoplasma (IF: 1,961)

Homayounfar K, König S, Rabe C, Beck-Broichsitter B, Lützen U, Ghadimi MB, Schmidt C (2016) Recruiting and Personal Development in Surgical Departments of Large Referral Centers - Current Practice and Options for Improvement from Industry and Service Business. Zentralbl Chir 2016 Jun 23. [Epub ahead of print] (IF: 0,638)

Lützen U, Kaschwich M, Zhao Y, Tjiong A, Marx M, Haenisch S, Wiedow O, Preuss S, Culman J, Zuhayra M (2016) Biodistribution and pharmacokinetics of the 99mTc labeled human elastase inhibitor, elafin, in rats. Drug Metab Pharmacokinet (2): 146-55. (IF: 2,568)

Lützen U, Naumann CM, Dischinger J, Baumann R, Marx M, Zhao Y, Jüptner M, Osmonov D, Knüpfer S, Jünemann KP, Zuhayra M (2016) 10-Year experience regarding the reliability, morbidity and associated radiation exposure of medical staff in radio-guided lymph node biopsy in penile cancer patients. BMC Urol 16(1): 47. (IF: 1,606)

Lützen U, Naumann CM, Marx M, Zhao Y, Jüptner M, Baumann R, Papp L, Zsótér N, Aksenov A, Jünemann KP, Zuhayra M (2016) A study on the value of computer-assisted assessment for SPECT/CT-scans in sentinel lymph node diagnostics of penile cancer as well as clinical reliability and morbidity of this procedure. Cancer Imaging 16(1):29 (IF: 1.470)

Lützen U, Zhao Y, Marx M, Imme T, Assam I, Siebert FA, Culman J, Zuhayra M (2016) Effective Method of Measuring the Radioactivity of [131 I]-Capsule prior to Radioiodine Therapy with Significant Reduction of the Radiation Exposure to the Medical Staff. J Appl Clin Med Phys 17(4): 5942. (IF: 1,172)

Lützen U, Zuhayra M,, Marx M, Zhao Y, Colberg C, Knüpfer S, Baumann R, Kähler KC, Jünemann KP, Naumann CM (2016) Value and efficiency of sentinel lymph node diagnostics in patients with penile carcinoma with palpable inguinal lymph nodes as a new multimodal, minimally invasive approach. Eur J Nucl Med Mol Imaging 43(13): 2313-2323. (IF:5,537)

Lützen U, Zuhayra M, Marx M, Zhao Y, Knüpfer S, Colberg C, Jünemann KP, NaumannCM (2016) Value and Efficacy of Sentinel Lymph Node Diagnostics in Patients with Penile  Carcinoma with Non-Palpable Inguinal Lymph Nodes: 5 Year-Follow-up, Clinical Nuclear Medicine. Clin Nucl Med 41(8): 621-5. (IF: 3.931)

Naumann CM, Bothe K, Munk-Hartig AK, van der Horst C, Massad H, Lützen U, Jünemann KP, Franz Hamann M. (2016) Long-term results of sentinel node biopsy diagnostics in penile carcinoma : Dynamic sentinel node biopsy in cases with nonpalpable lymph nodes in the groin. Urologe A 55(5): 641-4. (IF: 0,331)

Rahbar K, Ahmadzadehfar H, Kratochwil C, Haberkorn U, Schäfers M, Essler M, Baum RP, Kulkarani HR, Schmidt M, Bartenstein P, Pfestroff A, Lützen U, Marx M, Prasad V, Brenner W, Heinzel A, Ruf J, Meyer PT, Heuschkel M, Eveslage M, Bögemann M, Fendler WP, Krause BJ (2016) German multicenter study investigating 177Lu-PSMA-617 radioligand therapy in advanced prostate cancer patients. J Nucl Med. 2016 Oct 20. [Epub ahead of print] (IF: 5,849)

Fendler WP, Kratochwil C, Ahmadzadehfar H, Rahbar K, Baum RP, Schmidt M, Pfestroff A, Lützen U, Prasad V, Heinzel A, Heuschkel M, Ruf J, Bartenstein P, Krause BJ (2016) 177Lu-PSMA-617 therapy, dosimetry and follow-up in patients with metastatic castration-resistant prostate cancer. Nuklearmedizin 55(3):123-8.

Wiltfang J, Acil Y, Egberts H, Lützen U, Rohnen M, Naujokat H (2016) Man as a living bioreactor: Prefabrication of a custom vascularised bone graft in the gastrocolic omentum. Tissue Eng Part C Methods (8):740-6.

Lützen U, Zhao Y, Fritsch J, Zuhayra M, Schütze S, Steckelings UM, Recarti C, Namsolleck P, Unger T, Culman J (2015) Activation of intracellular angiotensin AT2 receptors induces rapid cell death in human uterine leiomyosarcoma cells. Clin Sci 128(9): 567-78. (IF: 5.629)

Naumann CM, van der Horst S, van der Horst C, Kähler KC, Seeger M, Osmonov D, Lützen U, Jünemann KP, Franz Hamann M (2015) Reliability of dynamic sentinel node biopsy combined with ultrasound-guided removal of sonographically suspicious lymph nodes as a diagnostic approach in patients with penile cancer with palpable inguinal lymph nodes. Urol Oncol 33(9): 389.e9-14. (IF: 3.363)

Lützen U, Zuhayra M, Marx M (2015) Konventionelle nuklearmedizinische Diagnostik der Lunge - Normalbefunde. Der Nuklearmediziner 38:48-55.

Cohrs B, Zhao Y, Lützen U, Culman J, Clement B, Zuhayra M (2014) In vivo SPECT imaging of [(123)I]-labeled pentamidine pro-drugs for the treatment of human African trypanosomiasis, pharmacokinetics, and bioavailability studies in rats. Int J Pharm 477(1-2): 167–75. (IF: 3.785)

Lützen U, Henze E (2014) Radio-Tympano-Sinu-Orthesis as a Treatment Option in Chronic Otitis Media and Paranasal Mucositis. In: Baum RP, editor. Therapeutic Nuclear Medicine Springer Berlin Heidelberg; 2014. p. 215–21.

Fuchs J, Hamann MF, Schulenburg F, Knüpfer S, Osmonov D, Lützen U, Jünemann KP, Naumann CM (2013) Sentinel lymph node biopsy for penile carcinoma : Assessment of reliability. Urologe A 52(10): 1447–50. (IF:0,436)

Bandi P, Zsoter N, Wirth A, Luetzen U, Derlin T, Papp L (2012) New workflows and algorithms of bone scintigraphy based on SPECT-CT. Conf Proc IEEE Eng Med Biol Soc. 2012:5971–4.

Bauman G, Lützen U, Ullrich M, Gaass T, Dinkel J, Elke G, Meybohm P, Frerichs I, Hoffmann B, Borggrefe J, Knuth HC, Schupp J, Prüm H, Eichinger M, Puderbach M, Biederer J, Hintze C (2011) Pulmonary functional imaging: qualitative comparison of Fourier decomposition MR imaging with SPECT/CT in porcine lung. Radiology 260(2): 551–9. (IF: 5.726)

Hutchinson JA, Riquelme P, Sawitzki B, Tomiuk S, Miqueu P, Zuhayra M, Oberg H, Pascher A, Lützen U, Janßen U, Broichhausen C, Renders L, Thaiss F, Scheuermann E, Henze E, Volk H, Chatenoud L, Lechler R, Wood K, Kabelitz D, Schlitt H, Geissler E, Fändrich F (2011) Cutting Edge: Immunological consequences and trafficking of human regulatory macrophages administered to renal transplant recipients. J Immunol 187(5): 2072–8. (IF: 5.788)

Zuhayra M, Zhao Y, von Forstner C, Henze E, Gohlke P, Culman J, Lützen U (2011) Activation of cerebral peroxisome proliferator-activated receptors γ (PPARγ) reduces neuronal damage in the substantia nigra after transient focal cerebral ischaemia in the rat. Neuropathol Appl Neurobiol 37(7): 738–52. (IF: 3.495)

Papp L, Zsoter N, Bandi P, Barna S, Luetzen U (2011) An extended registration framework for the triple registration of IBZM SPECT, DATSCAN SPECT and MRI brain images to support the evaluation of brain dopamine receptor scintigraphies. Conf Proc IEEE Eng Med Biol Soc. 2011:8025–8.

Papp L, Zsoter N, Loh C, Ole B, Egeler B, Garai I, Luetzen U (2011) Automated lymph node detection and classification on breast and prostate cancer SPECT-CT images. Conf Proc IEEE Eng Med Biol Soc.2011:3431–4.

Reese R, Herzog J, Falk D, Lützen U, Pinsker MO, Mehdorn HM, Ebersbach G,  Deuschl G, Volkmann J (2011) Successful deep brain stimulation in a case of posttraumatic tremor and hemiparkinsonism. Mov Disord 26(10):1954–5.

Mönig H., Hubold C., Lützen U., Hartmann J, Bröring D., Schrader C (2010) Eine Herausforderung für die interdisziplinäre Zusammenarbeit, Schleswig-Holsteinisches Ärzteblatt 63(12): 52-57

Zuhayra M, Alfteimi A, Forstner CV, Lützen U, Meller B, Henze E (2009) New approach for the synthesis of [18F]fluoroethyltyrosine for cancer imaging: simple, fast, and high yieldingautomated synthesis. Bioorg Med Chem 17(21): 7441–8. (IF: 2,822)

Papp L, Zuhayra M, Henze E, Luetzen U (2009) Extended Normalized Mutual Information for Lung SPECT - CT Registration. 3rd International Conference on Bioinformatics and Biomedical Engineering, ICBBE 2009. p. 1–3.

Hautmann S, Beitz S, Naumann M, Lützen U, Seif C, Stübinger SH, van der Horst C,  Braun PM, Leuschner I, Henze E, Jünemann KP (2008) Extended sentinel lymph node dissection in radical prostatectomy for prostate cancer: a study in the Kiel risk population. Urologe A 47(3): 299–303. (IF: 0,391)

Zuhayra M, Alfteimi A, Papp L, Lützen U, Lützen A, Von Forstner C, Meller B, Henze E (2008) Simplified fast and high yielding automated synthesis of [18F]fluoroethylcholine for prostate cancer imaging. Bioorg Med Chem 16(20): 9121–6. (IF: 3,075)

Zuhayra M, Lützen U, Lützen A, Papp L, Henze E, Friedrichs G, Oberdorfer (2008) F. C-H bond activation of coordinated pyridine: ortho-pyridyl-ditechnetiumhydridocarbonyl metal cyclus. Crystal structure and dynamic behavior in solution. Inorg Chem 47(21): 10177–82. (IF: 4,657)

Schultze J, Both M, Lützen U (2007) Aspects of imaging in radiation oncology with special reference to brachytherapy. NOWOTWORY Journal of Oncology 57(4): 149e–154e (IF: 0,200)

Kampen W, Oltmanns E, Czech N, Lützen U, Brenner W (2006) Quantifizierung des Knochenstoffwechsels in der konventionellen Skelettszintigraphie. Der Nuklearmediziner (4):249–54.

Lützen U, Engellandt K (2006) Late distant metastases of intracranial hemangiopericytomas. Röntgenpraxis 56(3):93–7.

Warnke PH, Wiltfang J, Springer I, Acil Y, Bolte H, Kosmahl M, Russo P, Sherry E, Lützen U, Wolfart S, Terheyden H (2006) Man as living bioreactor: fate of an exogenously prepared customized tissue-engineered mandible. Biomaterials (17):3163–7.

Lützen U (2004) Posterior reversible encephalopathy syndrome (PRES) in the framework of hypertensive encephalopathy. Röntgenpraxis 55(4):152–4.