Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma.
Choueiri TK, Tomczak P, Park SH, Venugopal B, Ferguson T, Chang YH, Hajek J, Symeonides SN, Lee JL, Sarwar N, Thiery-Vuillemin A, Gross-Goupil M, Mahave M, Haas NB, Sawrycki P, Gurney H, Chevreau C, Melichar B, Kopyltsov E, Alva A, Burke JM, Doshi G, Topart D, Oudard S, Hammers H, Kitamura H, Bedke J, Perini RF, Zhang P, Imai K, Willemann-Rogerio J, Quinn DI, Powles T; KEYNOTE-564 Investigators.N Engl J Med. 2021 Aug 19;385(8):683-694. doi: 10.1056/NEJMoa2106391.PMID: 34407342
Apalutamide in Patients With Metastatic Castration-Sensitive Prostate Cancer: Final Survival Analysis of the Randomized, Double-Blind, Phase III TITAN Study.
Chi KN, Chowdhury S, Bjartell A, Chung BH, Pereira de Santana Gomes AJ, Given R, Juárez A, Merseburger AS, Özgüroğlu M, Uemura H, Ye D, Brookman-May S, Mundle SD, McCarthy SA, Larsen JS, Sun W, Bevans KB, Zhang K, Bandyopadhyay N, Agarwal N.J Clin Oncol. 2021 Jul 10;39(20):2294-2303. doi: 10.1200/JCO.20.03488. Epub 2021 Apr 29.PMID: 33914595 Clinical Trial.
Genomic Testing in Patients with Metastatic Castration-resistant Prostate Cancer: A Pragmatic Guide for Clinicians.
Merseburger AS, Waldron N, Ribal MJ, Heidenreich A, Perner S, Fizazi K, Sternberg CN, Mateo J, Wirth MP, Castro E, Olmos D, Petrylak DP, Chowdhury S.Eur Urol. 2021 Apr;79(4):519-529. doi: 10.1016/j.eururo.2020.12.039. Epub 2021 Jan 23.PMID: 33494937
Advanced prostate cancer.
Hupe MC, Merseburger AS.World J Urol. 2021 Feb;39(2):295-296. doi: 10.1007/s00345-021-03618-4.PMID: 33591380
[Diagnostic markers in urology].
Hupe MC, Hempel MC, Rodler S, Frantzi M, Mischak H, Merseburger AS, Stief CG, Chaloupka M.Urologe A. 2021 Oct;60(10):1323-1330. doi: 10.1007/s00120-021-01568-8.PMID: 34156515 Review.
Adverse events of different chemotherapy regimens in the first-line treatment of patients with advanced or metastatic urothelial cancer: A systematic review and network meta-analysis of randomized controlled trials.
Laukhtina E, Mori K, Mostafaei H, Merseburger AS, Nyirady P, Moschini M, Quhal F, Pradere B, Motlagh RS, Enikeev D, Shariat SF; European Association of Urology–Young Academic Urologists Urothelial Carcinoma Working Group (EAU-YAU).Semin Oncol. 2021 Jun;48(3):181-192. doi: 10.1053/j.seminoncol.2021.09.005. Epub 2021 Oct 2.PMID: 34749886
[Cardiovascular side effects in patients undergoing androgen deprivation therapy: superiority of gonadotropin-releasing hormone antagonists? An update].
von Amsberg G, Thiele H, Merseburger A.Urologe A. 2021 Nov;60(11):1450-1457. doi: 10.1007/s00120-021-01583-9. Epub 2021 Jul 2.PMID: 34213627
A Global Trend Analysis of Kidney Cancer Incidence and Mortality and Their Associations with Smoking, Alcohol Consumption, and Metabolic Syndrome.
Huang J, Leung DK, Chan EO, Lok V, Leung S, Wong I, Lao XQ, Zheng ZJ, Chiu PK, Ng CF, Wong JH, Volpe A, Merseburger AS, Powles T, Teoh JY, Wong MCS.Eur Urol Focus. 2021 Jan 23:S2405-4569(21)00001-8. doi: 10.1016/j.euf.2020.12.020. Online ahead of print.PMID: 33495133
HYAL4-V1/Chondroitinase (Chase) Drives Gemcitabine Resistance and Predicts Chemotherapy Failure in Patients with Bladder Cancer.
Hasanali SL, Morera DS, Racine RR, Hennig M, Ghosh S, Lopez LE, Hupe MC, Escudero DO, Wang J, Zhu H, Sarcan S, Azih I, Zhou M, Jordan AR, Terris MK, Kuczyk MA, Merseburger AS, Lokeshwar VB.Clin Cancer Res. 2021 Aug 1;27(15):4410-4421. doi: 10.1158/1078-0432.CCR-21-0422. Epub 2021 May 24.PMID: 34031055
CDK19 as a diagnostic marker for high-grade prostatic intraepithelial neoplasia.
Offermann A, Joerg V, Hupe MC, Becker F, Müller M, Brägelmann J, Kirfel J, Merseburger AS, Sailer V, Tharun L, Perner S.Hum Pathol. 2021 Nov;117:60-67. doi: 10.1016/j.humpath.2021.07.006. Epub 2021 Jul 24.PMID: 34314763
Chemotherapy is superior to checkpoint inhibitors after radical surgery for urothelial carcinoma: a systematic review and network meta-analysis of oncologic and toxicity outcomes.
Laukhtina E, Sari Motlagh R, Mori K, Katayama S, Rajwa P, Yanagisawa T, Quhal F, Mostafaei H, Grossmann NC, König F, Aydh A, Pradere B, Resch I, Merseburger AS, Enikeev D, Shariat SF.Crit Rev Oncol Hematol. 2022 Jan;169:103570. doi: 10.1016/j.critrevonc.2021.103570. Epub 2021 Dec 10.PMID: 34902554
Risk Factors for a Complicated Postoperative Course in Flexible Ureteroscopy.
Ozimek T, Hochguertel L, Hupe MC, Struck JP, Wiessmeyer JR, Gilbert N, Merseburger AS, Kramer MW.Urol Int. 2021;105(7-8):611-618. doi: 10.1159/000512892. Epub 2021 Feb 17.PMID: 33596569
Analysis of tripartite motif (TRIM) family gene expression in prostate cancer bone metastases.
Offermann A, Kang D, Watermann C, Weingart A, Hupe MC, Saraji A, Stegmann-Frehse J, Kruper R, Schüle R, Pantel K, Taubert H, Duensing S, Culig Z, Aigner A, Klapper W, Jonigk D, Philipp Kühnel M, Merseburger AS, Kirfel J, Sailer V, Perner S.Carcinogenesis. 2021 Dec 31;42(12):1475-1484. doi: 10.1093/carcin/bgab083.PMID: 34487169
Partial Response and Stable Disease Correlate with Positive Outcomes in Atezolizumab-treated Patients with Advanced Urinary Tract Carcinoma.
Bedke J, Merseburger AS, Loriot Y, Castellano D, Choy E, Duran I, Rosenberg JE, Petrylak DP, Dreicer R, Perez-Gracia JL, Hoffman-Censits JH, Van Der Heijden MS, Pavlova J, Thiebach L, de Ducla S, Fear S, Powles T, Sternberg CN.Eur Urol Focus. 2021 Sep;7(5):1084-1091. doi: 10.1016/j.euf.2020.10.009. Epub 2020 Nov 6.PMID: 33168461
Response to Rucaparib in BRCA-Mutant Metastatic Castration-Resistant Prostate Cancer Identified by Genomic Testing in the TRITON2 Study.
Loehr A, Patnaik A, Campbell D, Shapiro J, Bryce AH, McDermott R, Sautois B, Vogelzang NJ, Bambury RM, Voog E, Zhang J, Piulats JM, Hussain A, Ryan CJ, Merseburger AS, Daugaard G, Heidenreich A, Fizazi K, Higano CS, Krieger LE, Sternberg CN, Watkins SP, Despain D, Simmons AD, Dowson M, Golsorkhi T, Chowdhury S, Abida W.Clin Cancer Res. 2021 Dec 15;27(24):6677-6686. doi: 10.1158/1078-0432.CCR-21-2199. Epub 2021 Oct 1.PMID: 34598946
Hemopatch® as a Hemostatic Agent is Safe in Partial Nephrectomy: A Large, Single-Surgeon Retrospective Evaluation.
Hupe MC, Büttner M, Tabrizi PF, Merseburger AS, Kuczyk MA, Imkamp F.Adv Ther. 2021 Feb;38(2):1024-1034. doi: 10.1007/s12325-020-01584-8. Epub 2020 Dec 4.PMID: 33277680
Pooled Analysis on the Effectiveness and Safety of Lipegfilgrastim in Patients With Urological Malignancies in the Real-World Setting.
Merseburger AS, Geiges G, Klier J, Wiesholzer M, Pichler P.Front Oncol. 2021 May 28;11:655355. doi: 10.3389/fonc.2021.655355. eCollection 2021.PMID: 34123810
Bicentric Retrospective Analysis of en Bloc Resection and Muscularis Mucosae Detection Rate in Non-Muscle Invasive Bladder Tumors: A Real-World Scenario.
Struck JP, Kramer MW, Katzendorn O, Hupe MC, Ozimek T, Hennig MJP, Wießmeyer JR, von Klot CAJ, Kuczyk MA, Kreipe HH, Merseburger AS, Perner S, Dressler FF.Adv Ther. 2021 Jan;38(1):258-267. doi: 10.1007/s12325-020-01529-1. Epub 2020 Oct 22.PMID: 33094476
SAUL, a single-arm study of atezolizumab for chemotherapy-pretreated locally advanced or metastatic carcinoma of the urinary tract: outcomes by key baseline factors, PD-L1 expression and prior platinum therapy.
Bamias A, Merseburger AS, Loriot Y, James N, Choy E, Castellano D, Lopez-Rios F, Calabrò F, Kramer M, de Velasco G, Zakopoulou R, Tzannis K, Sternberg CN.ESMO Open. 2021 Jun;6(3):100152. doi: 10.1016/j.esmoop.2021.100152. Epub 2021 May 10.PMID: 33984672
RLC score (R status, lymphovascular invasion, C-reactive protein) predicts survival following radical cystectomy for muscle-invasive bladder cancer.
Struck JP, Hupe MC, Heinisch A, Ozimek T, Hennig MJP, Klee M, von Klot C, Kalogirou C, Kuczyk MA, Merseburger AS, Kramer MW.Aktuelle Urol. 2021 Jan 14. doi: 10.1055/a-1310-3583. Online ahead of print.PMID: 33445183 English.
Plasma tumor gene conversions after one cycle abiraterone acetate for metastatic castration-resistant prostate cancer: a biomarker analysis of a multicenter international trial.
Jayaram A, Wingate A, Wetterskog D, Wheeler G, Sternberg CN, Jones R, Berruti A, Lefresne F, Lahaye M, Thomas S, Gormley M, Meacham F, Garg K, Lim LP, Merseburger AS, Tombal B, Ricci D, Attard G.Ann Oncol. 2021 Jun;32(6):726-735. doi: 10.1016/j.annonc.2021.03.196. Epub 2021 Mar 29.PMID: 33794293
Clinical recommendations in the management of advanced prostate cancer: International Gastrointestinal, Liver and Uro-oncology (IGILUC 2019) experts.
Elghazaly H, Mottet N, Garcia J, Oudard S, Roach M, Abbou C, Merseburger A, Emara A, Shehata S, Tawfik H, Khorshid O, Selim A, Assem A, Abdelkarim K, Ezz El-Arab L, Bazarbashi S, Omar A, Elwakil H, Elashry M, Abou ElFotouh M, Osman T, Ezz El Din M.World J Urol. 2021 May;39(5):1421-1429. doi: 10.1007/s00345-020-03328-3. Epub 2020 Jul 8.PMID: 32643031
Comprehensive Nomogram for Prediction of the Uric Acid Composition of Ureteral Stones as a Part of Tailored Stone Therapy.
Wiessmeyer JR, Ozimek T, Struck JP, Hupe MC, Willig J, Merseburger AS, Kramer MW.Eur Urol Focus. 2021 Feb 12:S2405-4569(21)00044-4. doi: 10.1016/j.euf.2021.02.001. Online ahead of print.PMID: 33589393
[TITAN study: evaluation of apalutamide in patients with metastatic hormone-sensitive prostate cancer - Treatment of metastatic hormone-sensitive prostate cancer (mHSPC)].
Merseburger AS, Suttmann H.Aktuelle Urol. 2021 Apr;52(2):155-160. doi: 10.1055/a-1076-3036. Epub 2020 Oct 28.PMID: 33113571
Safety and Efficacy of Atezolizumab in Understudied Populations with Pretreated Urinary Tract Carcinoma: Subgroup Analyses of the SAUL Study in Real-World Practice.
Merseburger AS, Castellano D, Powles T, Loriot Y, Retz M, Voortman J, Huddart RA, Gedye C, Van Der Heijden MS, Gurney H, Ong M, de Ducla S, Pavlova J, Fear S, Sternberg CN.J Urol. 2021 Aug;206(2):240-251. doi: 10.1097/JU.0000000000001768. Epub 2021 Apr 9.PMID: 33835866 Clinical Trial.
Does the Identification of a Minimum Number of Cases Correlate With Better Adherence to International Guidelines Regarding the Treatment of Penile Cancer? Survey Results of the European PROspective Penile Cancer Study (E-PROPS).
Lebentrau S, Wakileh GA, Schostak M, Schmid HP, Suarez-Ibarrola R, Merseburger AS, Hutterer GC, Necknig UH, Rink M, Bögemann M, Kluth LA, Pycha A, Burger M, Brookman-May SD, Bründl J, May M.Front Oncol. 2021 Nov 29;11:759362. doi: 10.3389/fonc.2021.759362. eCollection 2021.PMID: 34912711
New computed tomographic predictors of complicated perioperative course of 17.5F mini-percutaneous nephrolithotomy (mini-PNL).
Ozimek T, Laturnus JM, Gohlke C, Wiessmeyer JR, Struck JP, Hupe MC, Merseburger AS, Kramer MW.World J Urol. 2021 Jun;39(6):2147-2154. doi: 10.1007/s00345-020-03388-5. Epub 2020 Aug 9.PMID: 32772148
[A retrospective comparison of robotic assisted and conventional laparoscopic pyeloplasty in two centres].
Griessner H, Oberhammer L, Pallauf M, Oswald D, Kunit T, Colleselli D, Merseburger A, Kramer M, Lusuardi L, Mitterberger M.Urologe A. 2021 Apr;60(4):491-495. doi: 10.1007/s00120-020-01414-3. Epub 2020 Dec 8.PMID: 33294939
Why is the principle of "as much radicality as needed, as much organ preservation as possible" only insufficiently implemented in daily practice in the surgical treatment of penile cancer patients?
May M, Rink M, Merseburger AS, Brookman-May SD.Transl Androl Urol. 2020 Oct;9(5):1901-1903. doi: 10.21037/tau-20-1152.PMID: 33209653
Apalutamide plus Androgen Deprivation Therapy for Metastatic Castration-Sensitive Prostate Cancer: Analysis of Pain and Fatigue in the Phase 3 TITAN Study.
Agarwal N, McQuarrie K, Bjartell A, Chowdhury S, Pereira de Santana Gomes AJ, Chung BH, Özgüroğlu M, Juárez Soto Á, Merseburger AS, Uemura H, Ye D, Given R, Basch E, Miladinovic B, Lopez-Gitlitz A, Chi KN.J Urol. 2021 Oct;206(4):914-923. doi: 10.1097/JU.0000000000001841. Epub 2021 May 27.PMID: 34039013
Adverse events of the second-line treatment for patients with locally advanced or metastatic urothelial carcinoma of the bladder: network meta-analysis.
Laukhtina E, Mori K, Mostafaei H, Merseburger AS, Nyirady P, Moschini M, Quhal F, Schuettfort VM, Pradere B, Motlagh RS, Enikeev D, Shariat SF, Of Urology-Young Academic Urologists Eau-Yau Urothelial Carcinoma Working Group EA.Immunotherapy. 2021 Aug;13(11):917-929. doi: 10.2217/imt-2020-0305. Epub 2021 Jun 3.PMID: 34078134
[Osteoprotection in the management of metastatic prostate cancer: real-world data from Germany and decision guidance].
Hupe MC, Müller M, Struck JP, Wießmeyer JR, Ozimek T, Steuber T, Gschwend J, Hammerer P, Kramer MW, Merseburger AS.Aktuelle Urol. 2022 Feb;53(1):43-53. doi: 10.1055/a-1332-8625. Epub 2021 Jun 1.PMID: 34062565
Impact of COVID-19 crisis on medical care of patients with metastasized uro-oncologic disease under systemic cancer therapy: a multicenter study in German university hospitals.
Struck JP, Schnoor M, Schulze A, Hupe MC, Ozimek T, Oppolzer IA, Schnabel MJ, Burger M, Darr C, Gruenwald V, Hadaschik B, Weinke M, Kuebler H, Klockenbusch JC, Grabbert MT, Gratzke C, Kramer MW, Katalinic A, Merseburger AS.World J Urol. 2021 Nov 30:1-10. doi: 10.1007/s00345-021-03868-2. Online ahead of print.PMID: 34850270
[Intravesical Gemcitabine instillations following BCG failure and allergy to Mitomycin: A unique case of a patient with an inverted papilloma of the bladder].
Matzen M, Offermann A, Tharun L, Perner S, Merseburger AS, Kramer M, Hupe MC.Aktuelle Urol. 2021 Feb;52(1):43-46. doi: 10.1055/a-1312-9032. Epub 2021 Feb 1.PMID: 33525029.
Nomograms including the UBC® Rapid test to detect primary bladder cancer based on a multicentre dataset.
Meisl CJ, Karakiewicz PI, Einarsson R, Koch S, Hallmann S, Weiß S, Hemdan T, Malmström PU, Styrke J, Sherif A, Hasan MN, Pichler R, Tulchiner G, Palou J, Rodríguez Faba Ó, Hennenlotter J, Stenzl A, Ritter R, Niegisch G, Grunewald CM, Schlomm T, Friedersdorff F, Barski D, Otto T, Gössl A, Arndt C, Esuvaranathan K, Kesavan NR, Zhijiang Z, Kramer MW, Hennig MJP, Ecke TH.BJU Int. 2021 Dec 20. doi: 10.1111/bju.15677. Online ahead of print.PMID: 34928524
[Current practice patterns of perioperative cystectomy management in Germany: a questionnaire survey].
Dressler FF, Dogan S, Hennig M, Frank T, Struck J, Cebulla A, Salem J, Borgmann H, Klatte T, Kramer MW, Hofbauer S.Aktuelle Urol. 2021 Feb;52(1):82-87. doi: 10.1055/a-1025-2523. Epub 2020 Jul 29.PMID: 32726815
Discrepancy between German S3 Guideline Recommendations and Daily Urologic Practice in the Management of Nonmuscle Invasive Bladder Cancer: Results of a Binational Survey.
Struck JP, Hennig MJP, Hupe MC, Moharam N, Paffenholz P, Nestler T, Frank T, Worst TS, Grabbert M, Pohlmann PF, Dogan S, Hofbauer SL, Kalogirou C, Mattigk A, Brandt MP, Krabbe LM, Reis H, Dressler FF, Kramer MW, Salem J.Urol Int. 2021 Aug 31:1-11. doi: 10.1159/000518166. Online ahead of print.PMID: 34515257
[Implementation of the new collective agreement in 2021 in urological clinics : Expectations and reality].
Stahl L, Struck JP, König J, Braun M, Westphal J.Urologe A. 2021 Dec 22. doi: 10.1007/s00120-021-01736-w. Online ahead of print.PMID: 34935996
[Great potential, little substance : Overview of quality and quantity of urological apps in the German app store].
Mattigk A, Bellut L, Albrecht UV, von Jan U, Struck JP.Urologe A. 2021 Dec 3. doi: 10.1007/s00120-021-01716-0. Online ahead of print.PMID: 34862517
Increased Severe Adverse Outcomes and Decreased Emergency Room Visits for Pyelonephritis: First Report of Collateral Damage during COVID-19 Pandemic in Urology.
Borgmann H, Struck JP, Mattigk A, Wenzel M, Pilatz A, Kranz J, Weiten R, von Landenberg N, Spachmann PJ, Aksoy C, Haferkamp A, Boehm K.Urol Int. 2021;105(3-4):199-205. doi: 10.1159/000513458. Epub 2021 Jan 6.PMID: 33406523
Clinical impact of whole-body 68Ga-PSMA I&T PET/CT: lesion frequency and added benefit in lower extremities.
Stolzenbach LF, Löcherbach F, Wargenau K, Pose R, Steuber T, Tian Z, Budäus L, Tilki D, Graefen M, Köhler D, Karakiewicz PI, Sauer M, Apostolova II, Maurer T, Berliner C.Nuklearmedizin. 2021 Dec;60(6):417-424. doi: 10.1055/a-1542-6064. Epub 2021 Aug 20.PMID: 34416785
Correction: Clinical impact of whole-body 68Ga-PSMA I&T PET/CT: lesion frequency and added benefit in lower extremities.
Stolzenbach LF, Löcherbach F, Wargenau K, Pose R, Steuber T, Tian Z, Budäus L, Tilki D, Graefen M, Köhler D, Karakiewicz PI, Sauer M, Apostolova II, Maurer T, Berliner C.Nuklearmedizin. 2021 Sep 3. doi: 10.1055/a-1626-6669. Online ahead of print.PMID: 34479375