development and optimization of new antibodies/antibody derivatives for the therapy of various tumor entities and autoimmune diseases
improving the recruitment and activation of immune cells by antibodies/antibody derivatives, e.g., by Fc engineering
generation of antibodies for cellular immunotherapy
production and characterization of different antibody formats in order to evaluate the optimal design for the most effective tumor therapy
generation of immunotoxins and antibody-drug conjugates
identification of new target structures on tumor cells by phage display
in vivo mouse models to study the effectiveness of new antibodies/antibody derivatives